利福布汀诱发的葡萄膜炎伴炎性玻璃体浸润。
Rifabutin-induced uveitis with inflammatory vitreous infiltrate.
作者信息
Khan M A, Singh J, Dhillon B
机构信息
Princess Alexandra Eye Pavilion, Edinburgh, UK.
出版信息
Eye (Lond). 2000 Jun;14 ( Pt 3A):344-6. doi: 10.1038/eye.2000.85.
PURPOSE
To describe an ocular complication of rifabutin therapy in the treatment of Mycobacterium avium complex (MAC) infection in the absence of HIV infection or AIDS.
METHODS
Three patients on rifabutin therapy for MAC chest infection developed anterior uveitis with vitreous infiltrates. The clinical course and visual outcome are discussed.
RESULTS
The ocular signs of anterior segment inflammation along with vitreous infiltrate resolved on topical steroid therapy without long-term visual sequelae.
CONCLUSION
This report highlights the potential of uveitis in patients treated for MAC infection with rifabutin without concurrent HIV infection or AIDS.
目的
描述在无人类免疫缺陷病毒（HIV）感染或获得性免疫缺陷综合征（AIDS）情况下，利福布汀治疗鸟分枝杆菌复合群（MAC）感染时出现的眼部并发症。
方法
3例接受利福布汀治疗MAC肺部感染的患者发生了伴有玻璃体浸润的前葡萄膜炎。讨论了临床病程和视力转归。
结果
局部应用类固醇治疗后，前段炎症的眼部体征及玻璃体浸润消退，未留下长期视力后遗症。
结论
本报告强调了在未合并HIV感染或AIDS的情况下，接受利福布汀治疗MAC感染的患者发生葡萄膜炎的可能性。
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