Shackney S E
J Natl Cancer Inst. 1975 Oct;55(4):811-20. doi: 10.1093/jnci/55.4.811.
A function was developed to relate the radioautographic detectability of tritiated thymidine to its incorporation into nuclear DNA under various experimental and specimen processing conditions. The implications of this function for the interpretation of cell kinetic studies were outlined, and its implications for radioautographic methodology were discussed. The standardization of radioautographic methods for facilitation of comparisons of data obtained from different sources under dissimilar experimental conditions was discussed.
开发了一种函数,用于关联在各种实验和样本处理条件下,氚标记胸腺嘧啶核苷的放射自显影可检测性与其掺入核DNA的情况。概述了该函数对细胞动力学研究解释的意义,并讨论了其对放射自显影方法学的意义。还讨论了放射自显影方法的标准化,以便于在不同实验条件下比较从不同来源获得的数据。