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放射自显影传递函数及其对放射自显影方法学的影响。

The radioautographic transfer function and its implications for radioautographic methodology.

作者信息

Shackney S E

出版信息

J Natl Cancer Inst. 1975 Oct;55(4):811-20. doi: 10.1093/jnci/55.4.811.

DOI:10.1093/jnci/55.4.811
PMID:1102720
Abstract

A function was developed to relate the radioautographic detectability of tritiated thymidine to its incorporation into nuclear DNA under various experimental and specimen processing conditions. The implications of this function for the interpretation of cell kinetic studies were outlined, and its implications for radioautographic methodology were discussed. The standardization of radioautographic methods for facilitation of comparisons of data obtained from different sources under dissimilar experimental conditions was discussed.

摘要

开发了一种函数,用于关联在各种实验和样本处理条件下,氚标记胸腺嘧啶核苷的放射自显影可检测性与其掺入核DNA的情况。概述了该函数对细胞动力学研究解释的意义,并讨论了其对放射自显影方法学的意义。还讨论了放射自显影方法的标准化,以便于在不同实验条件下比较从不同来源获得的数据。

相似文献

1
The radioautographic transfer function and its implications for radioautographic methodology.放射自显影传递函数及其对放射自显影方法学的影响。
J Natl Cancer Inst. 1975 Oct;55(4):811-20. doi: 10.1093/jnci/55.4.811.
2
Origin of calcified tissue in regenerating spines of the sea urchin, Strongylocentrotus purpuratus (Stimpson): a quantitative radioautographic study with tritiated thymidine.海胆紫球海胆(Stimpson)再生棘中钙化组织的起源:用氚标记胸腺嘧啶核苷进行的定量放射自显影研究
J Exp Zool. 1971 Oct;178(2):233-46. doi: 10.1002/jez.1401780208.
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Automated radioautographic grain counting. Correction for grain overlap.自动放射自显影片颗粒计数。颗粒重叠校正。
Cell Tissue Kinet. 1983 May;16(3):221-7.
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A radioautographic study of the developing periodontium of the rat.
Periodontics. 1966 Nov-Dec;4(6):297-301.
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[PROLIFERATIVE CAPACITY OF NORMAL BONE MARROW. (RADIOAUTOGRAPHIC STUDY WITH TRITIATED THYMIDINE)].[正常骨髓的增殖能力。(用氚标记胸腺嘧啶核苷的放射自显影研究)]
Stud Cercet Med Interna. 1965;40:165-70.
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Radioautographic studies of plaque-forming cells. I. Antigen-stimulated proliferation of plaque-forming cells.噬斑形成细胞的放射自显影研究。I. 抗原刺激下噬斑形成细胞的增殖
J Exp Med. 1968 Aug 1;128(2):235-57. doi: 10.1084/jem.128.2.235.
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The discrete phases of the cell cycle: autoradiographic, physical, and chemical evidences.细胞周期的离散阶段:放射自显影、物理和化学证据。
J Natl Cancer Inst. 1975 Oct;55(4):821-6. doi: 10.1093/jnci/55.4.821.
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[Radioautographic studies of the cell life cycle in spontaneous tumors of mammary glands in mice at different intensities of proliferation].
Tsitologiia. 1966 May-Jun;8(3):370-8.
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[Radioautographic study of the incorporation in vitro of tritiated thymidine into normal human skin and in certain epidermal proliferations].[氚标记胸腺嘧啶核苷体外掺入正常人皮肤及某些表皮增生性病变的放射自显影研究]
Pathol Eur. 1970:Suppl 1:1-197.
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[Morphologic and radioautographic study of DNA synthesis in rabbit oocytes at early stages of oogenesis].
Tsitologiia. 1972 May;14(5):558-67.

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