鸡肠球菌中的万古霉素耐药性与含丝氨酸的肽聚糖有关。
Vancomycin resistance is associated with serine-containing peptidoglycan in Enterococcus gallinarum.
作者信息
Grohs P, Gutmann L, Legrand R, Schoot B, Mainardi J L
机构信息
Laboratoire de Recherche Moléculaire sur les Antibiotiques, UFR Broussais-Hôtel Dieu, Université Paris VI, Paris, France.
出版信息
J Bacteriol. 2000 Nov;182(21):6228-32. doi: 10.1128/JB.182.21.6228-6232.2000.
Abstract
In Enterococcus gallinarum SC1, a low-level vancomycin-resistant strain, only monomeric muropentapeptides with a C-terminal D-alanine were detected after growth without vancomycin. In contrast, in SC1 induced by vancomycin, as well as in AIB39, a constitutive vancomycin-resistant strain, monomeric and dimeric muropentapeptides with a C-terminal D-serine were detected.
摘要
在低水平耐万古霉素的鹑鸡肠球菌SC1中，在无万古霉素条件下生长后，仅检测到具有C端D - 丙氨酸的单体型胞壁五肽。相比之下，在由万古霉素诱导的SC1以及组成型耐万古霉素菌株AIB39中，检测到了具有C端D - 丝氨酸的单体型和二聚体型胞壁五肽。
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