沙眼衣原体中σ-54启动子的鉴定与定位
Identification and mapping of sigma-54 promoters in Chlamydia trachomatis.
作者信息
Mathews S A, Timms P
机构信息
Centre for Molecular Biotechnology, School of Life Sciences, Queensland University of Technology, Brisbane, Queensland, Australia.
出版信息
J Bacteriol. 2000 Nov;182(21):6239-42. doi: 10.1128/JB.182.21.6239-6242.2000.
Abstract
The first sigma(54) promoters in Chlamydia trachomatis L2 were mapped upstream of hypothetical proteins CT652.1 and CT683. Comparative genomics indicated that these sigma(54) promoters and potential upstream activation binding sites are conserved in orthologous C. trachomatis D, C. trachomatis mouse pneumonitis strain, and Chlamydia pneumoniae (CWL029 and AR39) genes.
摘要
沙眼衣原体L2中的首个σ⁵⁴启动子被定位在假定蛋白CT652.1和CT683的上游。比较基因组学表明，这些σ⁵⁴启动子和潜在的上游激活结合位点在沙眼衣原体D、沙眼衣原体小鼠肺炎菌株以及肺炎衣原体（CWL029和AR39）的直系同源基因中是保守的。
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