Baba M, Tatsuta M, Miya A, Ishida H, Masutani S, Kawasaki T, Satomi T, Hanai J, Kimura F
Department of Surgery, Kashiwara Municipal Hospital, 1-7-9 Houzenji, Kashiwara 582-0005, Japan.
Breast Cancer. 2000;7(2):173-5. doi: 10.1007/BF02967453.
We describe a case of a 58-year-old woman with right inguinal lymph node swelling and a T1 tumor in the right breast. She was referred with an 18-month history of the former complaint and a six-month history of the latter. Excisional biopsy of the inguinal lymph node revealed breast cancer metastasis. Radiographical examination showed no metastases to the lungs, liver or bone. Modified radical mastectomy was performed. Histological examination revealed solid tubular carcinoma, PT2, PM (axillary lymph node metastases 4/16), stage IV. Estrogen and progesterone receptors were negative. Three cycles of postoperative cyclophosphamide, adriamycin and 5-fluorouracil (CAF) chemotherapy were given, and the right inguinal area was irradiated with 40 Gy. The patient complained of swelling in both legs three years after surgery. Computed tomography revealed marked lymph node swellings in the pelvic cavity. She died six months later. Inguinal lymph node metastasis from breast cancer is very rare, although distant lymph node metastasis in the cervix occurs frequently. This case should help clarify how breast cancer metastasizes to distant lymph nodes.
我们描述了一例58岁女性患者，其右侧腹股沟淋巴结肿大，右乳有一个T1期肿瘤。她因前者有18个月的病史、后者有6个月的病史前来就诊。腹股沟淋巴结切除活检显示为乳腺癌转移。影像学检查未发现肺部、肝脏或骨骼转移。行改良根治性乳房切除术。组织学检查显示为实性管状癌，PT2，PM（腋窝淋巴结转移4/16），IV期。雌激素和孕激素受体均为阴性。术后给予三个周期的环磷酰胺、阿霉素和5-氟尿嘧啶（CAF）化疗，并对右侧腹股沟区进行40 Gy的放射治疗。患者术后三年出现双下肢肿胀。计算机断层扫描显示盆腔内有明显的淋巴结肿大。她在六个月后死亡。乳腺癌腹股沟淋巴结转移非常罕见，尽管宫颈癌远处淋巴结转移很常见。该病例应有助于阐明乳腺癌如何转移至远处淋巴结。
