Nagasawa M, Iino Y, Horiguchi J, Takei H, Maemura M, Horii Y, Matsumoto H, Nagaoka H, Oyama T, Nakajima T, Morishita Y
Second Department of Surgery, Gunma University School of Medicine, 3-39-15 Showa-machi, Maebashi, Gunma 371-8511, Japan.
Breast Cancer. 2000;7(2):176-8. doi: 10.1007/BF02967454.
A rare case of sudden hemorrhage caused by breast cancer is reported. A 71-year-old woman noted bleeding from her left breast. Physical examination of the left breast showed a localized open cavity accompanied by bleeding and coagulation. The patient had no history of breast trauma or anticoagulation therapy. Incisional biopsy followed by histological examination resulted in a diagnosis of granulation tissue with no cancer cells present. Mammography and ultrasonography indicated probable breast cancer. As a result, a second incisional biopsy was performed, which suggested invasive ductal carcinoma without histological skin invasion. A modified radical mastectomy was performed under a diagnosis of stage II breast cancer. Breast cancer with sudden hemorrhage is rare. We review the literature and discuss the cause of this unusual manifestation.
报告了一例罕见的由乳腺癌引起的突发性出血病例。一名71岁女性发现左侧乳房出血。左侧乳房体格检查显示有一个局限性开放腔隙，伴有出血和凝血。患者无乳房创伤或抗凝治疗史。切开活检并进行组织学检查后诊断为肉芽组织，未发现癌细胞。乳房X线摄影和超声检查提示可能为乳腺癌。因此，进行了第二次切开活检，结果提示为浸润性导管癌，无组织学上的皮肤侵犯。在诊断为II期乳腺癌后进行了改良根治性乳房切除术。乳腺癌伴突发性出血较为罕见。我们回顾了文献并讨论了这种不寻常表现的原因。
