Carter D C
Br J Surg. 1976 Oct;63(10):788-92. doi: 10.1002/bjs.1800631014.
Several new compounds have become available recently which are potent inhibitors of gastric secretion. The therapeutic potential of these inhibitors in the peptic ulcer diathesis is reviewed and it is concluded that the histamine H2-receptor antagonists show most promise at present. The prostaglandins and gastro-intestinal polypeptides are of considerable physiological interest but are unlikely to have clinical importance in the immediate future.
最近有几种新的化合物问世,它们是胃酸分泌的强效抑制剂。本文综述了这些抑制剂在消化性溃疡素质方面的治疗潜力,并得出结论:组胺H2受体拮抗剂目前显示出最大的前景。前列腺素和胃肠多肽具有相当大的生理意义,但在近期不太可能具有临床重要性。