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Treatment of solid tumours in children with tumour-lysate-pulsed dendritic cells.

作者信息

Geiger J, Hutchinson R, Hohenkirk L, McKenna E, Chang A, Mulé J

出版信息

Lancet. 2000 Sep 30;356(9236):1163-5. doi: 10.1016/S0140-6736(00)02762-8.

DOI:10.1016/S0140-6736(00)02762-8
PMID:11030299
Abstract

Dendritic cells are potent stimulators of antigen-specific immune responses, including antitumour responses. We explored the use of tumour-lysate-pulsed dendritic cells in children with relapsed solid tumours. Dendritic cell treatment in children was feasible and apparently not toxic. The treatment was able to produce significant tumour regression in a child with metastatic fibrosarcoma.

摘要

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