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两头患有麻疹病毒感染迹象的长须鲸(Balaenoptera physalus)的病理检查结果。

Pathological findings in two fin whales (Balaenoptera physalus) with evidence of morbillivirus infection.

作者信息

Jauniaux T, Charlier G, Desmecht M, Haelters J, Jacques T, Losson B, Van Gompel J, Tavernier J, Coignoul F

机构信息

Department of Pathology, Veterinary College, University of Liège, Sart Tilman B43, Liege, 4000, Belgium.

出版信息

J Comp Pathol. 2000 Aug-Oct;123(2-3):198-201. doi: 10.1053/jcpa.2000.0395.

Abstract

Two immature female fin whales stranded on the Belgian and French coastlines, were examined post mortem. The main gross findings were massive parasitic infestation, associated with a large thrombus in one whale, and severe emaciation. Microscopical investigations revealed multinucleated syncytia with large intranuclear inclusion bodies in various tissues, and positive immunolabelling for morbillivirus antigens. Other evidence of morbillivirus infection was provided by the demonstration of specific viral structures in syncytia and in cell cultures, and the detection of neutralizing antibodies to canine distemper virus. To the authors>> knowledge, this is the first firm report of morbillivirus infection in baleen whales.

摘要

对搁浅在比利时和法国海岸的两头未成年雌性长须鲸进行了尸检。主要大体检查结果为大量寄生虫感染,其中一头鲸鱼伴有一个大血栓,以及严重消瘦。显微镜检查显示,在各种组织中存在具有大核内包涵体的多核巨细胞,并且对麻疹病毒抗原进行免疫标记呈阳性。在多核巨细胞和细胞培养物中发现特异性病毒结构,以及检测到针对犬瘟热病毒的中和抗体,为麻疹病毒感染提供了其他证据。据作者所知,这是须鲸中麻疹病毒感染的第一份确凿报告。

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