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[Sweet综合征的全身表现:一例报告]

[Systemic manifestations of Sweet's syndrome: a case report].

作者信息

El Maghraoui A, Abouzahir A, Tabache F, Bezza A, Rimani M, Ghafir D, Ohayon V, Archane M I

机构信息

Service de Médecine B, Hôpital Militare d'Instruction Mohamed-V, Rabat, Maroc.

出版信息

Ann Med Interne (Paris). 2000 Sep;151(5):413-6.

Abstract

Sweet's syndrome belongs to the group of neutrophilic dermatoses. We report the case of a 36-year-old man admitted for stiff neck and fever. He had a history of recurrent oral aphtous ulcers, orchitis, phlebitis, two episodes of febrile acute polyarthritis with interstitial pneumonia. He presented a stiff neck and a temperature of 40 degrees C for two days associated with an erythematonodular eruption of the right periocular region. Laboratory exams showed an inflammatory syndrome with hyperleukocytosis. Skin biopsy showed dermic neutrophilic infiltrates, confirming the diagnosis of Sweet's syndrome. The patient improved dramatically with corticosteroids: the temperature fell and neck stiffness and skin lesions disappeared. In light of this case with a rich cohort of extracutaneous manifestations, we reviewed the literature on the characteristics of Sweet's syndrome. This syndrome is commonly associated with inflammatory and neoplastic diseases.

摘要

斯威特综合征属于嗜中性皮病组。我们报告一例36岁男性因颈部僵硬和发热入院的病例。他有复发性口腔阿弗他溃疡、睾丸炎、静脉炎病史,曾两次出现伴有间质性肺炎的发热性急性多关节炎。他出现颈部僵硬,体温40摄氏度,持续两天,并伴有右眼周区域的红斑结节性皮疹。实验室检查显示炎症综合征伴白细胞增多。皮肤活检显示真皮嗜中性粒细胞浸润,确诊为斯威特综合征。患者使用皮质类固醇后病情显著改善:体温下降,颈部僵硬和皮肤病变消失。鉴于该病例有丰富的皮肤外表现,我们回顾了关于斯威特综合征特征的文献。该综合征通常与炎症性和肿瘤性疾病相关。

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