Bariliak I R, Frolov V M, Pinskiĭ L L, Topol'nitskiĭ V S
Tsitol Genet. 2000 Jul-Aug;34(4):3-5.
The chromosomal apparatus of peripheral blood lymphocytes was studied in 19 patients with chronic hepatitis B (CHB) and 17 patients with chronic hepatitis C (CHC). Significant changes in cytogenetic indices were revealed in the both groups. Incidence of aberrant cells in CHC exceeded significantly that in CHB (15.3 +/- 1.5% vs 11.1 +/- 0.9% respectively; P < 0.05). Frequencies of aberration per cell and chromatid fragments were also significantly higher in CHC compared with both CHB and practically normal donor groups.
对19例慢性乙型肝炎（CHB）患者和17例慢性丙型肝炎（CHC）患者的外周血淋巴细胞染色体装置进行了研究。两组均发现细胞遗传学指标有显著变化。CHC中异常细胞的发生率显著高于CHB（分别为15.3±1.5%和11.1±0.9%；P<0.05）。与CHB组和实际正常供体组相比，CHC组中每个细胞的畸变频率和染色单体片段频率也显著更高。
