澳大利亚立克次体（斑点热群中差异最大的立克次体）的外膜蛋白A和B基因

The rickettsial outer-membrane protein A and B genes of Rickettsia australis, the most divergent rickettsia of the spotted fever group.

作者信息

Stenos J, Walker D H

出版信息

Int J Syst Evol Microbiol. 2000 Sep;50 Pt 5:1775-1779. doi: 10.1099/00207713-50-5-1775.

DOI:10.1099/00207713-50-5-1775

Abstract

The genes for rickettsial outer-membrane protein A (rOmpA), a distinguishing feature of spotted fever group (SFG) rickettsiae, and rOmpB, a genus-specific protein, were identified and sequenced in Rickettsia australis. The amino acid sequences of domains I, III and IV of the R. australis rOmpA share close homology with those of rOmpA of other SFG rickettsiae, but the repeat region (domain II) is dramatically different from that of other known SFG rOmpA. R. australis rOmpB is more similar to rOmpB of other SFG rickettsiae than to that of typhus group rickettsiae.

摘要

斑点热群（SFG）立克次体的一个显著特征——立克次体外膜蛋白A（rOmpA）基因，以及属特异性蛋白rOmpB基因，在澳大利亚立克次体中得到鉴定和测序。澳大利亚立克次体rOmpA的结构域I、III和IV的氨基酸序列与其他SFG立克次体的rOmpA具有高度同源性，但重复区域（结构域II）与其他已知的SFG rOmpA显著不同。与斑疹伤寒群立克次体的rOmpB相比，澳大利亚立克次体rOmpB与其他SFG立克次体的rOmpB更为相似。