Stenos J, Roux V, Walker D, Raoult D
Department of Pathology, University of Texas Medical Branch, Galveston 77550-0609, USA.
Int J Syst Bacteriol. 1998 Oct;48 Pt 4:1399-404. doi: 10.1099/00207713-48-4-1399.
The name Rickettsia honei, strain RBT, has been proposed for a unique spotted fever group (SFG) agent which is pathogenic for humans. This agent has previously been compared to the other SFG agents and was shown to be distinct in protein structure by SDS-PAGE and by immunoblotting. Genetic comparisons of the 16S rRNA, rompA, gltA and the 17 kDa antigen genes with the other SFG rickettsiae confirmed the phylogenetic distance between R. honei and the previously described species. Genetically, Rickettsia honei is more closely related to the Thai tick typhus (TT-118) rickettsia than to any other member of the SFG. Indeed, it is proposed that TT-118 is a strain of R. honei which was previously isolated in Thailand. These results elucidate the presence of a unique SFG rickettsial species in Australasia.
一种对人类致病的独特斑点热群（SFG）病原体被命名为霍氏立克次体（Rickettsia honei），菌株为RBT。此前已将该病原体与其他SFG病原体进行比较，通过SDS - PAGE和免疫印迹显示其蛋白质结构不同。对16S rRNA、rompA、gltA和17 kDa抗原基因与其他SFG立克次体进行基因比较，证实了霍氏立克次体与先前描述的物种之间的系统发育距离。在基因上，霍氏立克次体与泰国蜱传斑疹伤寒（TT - 118）立克次体的关系比与SFG的任何其他成员都更密切。事实上，有人提出TT - 118是霍氏立克次体的一个菌株，此前在泰国分离得到。这些结果阐明了在澳大拉西亚存在一种独特的SFG立克次体物种。
