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低频血氧水平依赖波动的相关性反映了皮质-皮质连接。

Correlations in low-frequency BOLD fluctuations reflect cortico-cortical connections.

作者信息

Lowe M J, Dzemidzic M, Lurito J T, Mathews V P, Phillips M D

机构信息

Department of Radiology, Indiana University School of Medicine, Indianapolis, Indiana, USA.

出版信息

Neuroimage. 2000 Nov;12(5):582-7. doi: 10.1006/nimg.2000.0654.

DOI:10.1006/nimg.2000.0654
PMID:11034865
Abstract

Cross-correlation of low-frequency temporal fluctuations (<0.08 Hz) was used to correlate widely separated anatomic regions during continuous performance of a spatial working memory task. The regions of highest correlation to right-hemisphere dorsolateral prefrontal cortex correspond to the regions of largest baseline signal change in a conventional block-style functional MRI paradigm. Additionally, it is shown that the correlations between elements of the functional network increase during performance of a task that activates the network when compared to a task that does not directly stimulate the functionally connected network.

摘要

在空间工作记忆任务的持续执行过程中,使用低频时间波动(<0.08 Hz)的互相关来关联广泛分离的解剖区域。与右半球背外侧前额叶皮层相关性最高的区域,对应于传统组块式功能磁共振成像范式中基线信号变化最大的区域。此外,研究表明,与不直接刺激功能连接网络的任务相比,在激活该网络的任务执行过程中,功能网络各元素之间的相关性会增加。

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