Sundararajan Raanju R, Bruce Scott A
Department of Statistics and Data Science, Southern Methodist University, Dallas, TX 75205, United States.
Department of Statistics, Texas A&M University, 155 Ireland Street, College Station, TX 77843, United States.
Biometrics. 2025 Jul 3;81(3). doi: 10.1093/biomtc/ujaf083.
Information from frequency bands in biomedical time series provides useful summaries of the observed signal. Many existing methods consider summaries of the time series obtained over a few well-known, pre-defined frequency bands of interest. However, there is a dearth of data-driven methods for identifying frequency bands that optimally summarize frequency-domain information in the time series. A new method to identify partition points in the frequency space of a multivariate locally stationary time series is proposed. These partition points signify changes across frequencies in the time-varying behavior of the signal and provide frequency band summary measures that best preserve nonstationary dynamics of the observed series. An $L_2$-norm based discrepancy measure that finds differences in the time-varying spectral density matrix is constructed, and its asymptotic properties are derived. New nonparametric bootstrap tests are also provided to identify significant frequency partition points and to identify components and cross-components of the spectral matrix exhibiting changes over frequencies. Finite-sample performance of the proposed method is illustrated via simulations. The proposed method is used to develop optimal frequency band summary measures for characterizing time-varying behavior in resting-state electroencephalography time series, as well as identifying components and cross-components associated with each frequency partition point.
生物医学时间序列中频段的信息为观测信号提供了有用的汇总。许多现有方法考虑的是在一些知名的、预先定义的感兴趣频段上获得的时间序列汇总。然而,缺乏用于识别能最佳汇总时间序列中频域信息的频段的数据驱动方法。本文提出了一种识别多元局部平稳时间序列频率空间中分割点的新方法。这些分割点表示信号时变行为在频率上的变化,并提供能最佳保留观测序列非平稳动态的频段汇总度量。构建了一种基于(L_2)范数的差异度量,用于发现时变频谱密度矩阵中的差异,并推导了其渐近性质。还提供了新的非参数自助法检验,以识别显著的频率分割点,并识别频谱矩阵中随频率变化的分量和交叉分量。通过模拟说明了所提方法的有限样本性能。所提方法用于开发用于表征静息态脑电图时间序列时变行为的最佳频段汇总度量,以及识别与每个频率分割点相关的分量和交叉分量。