Beckman N, Seghatchian J
National Blood Transfusion Service, Birmingham & North London, London and South East, London, NW9 5BG, Colindale, UK.
Transfus Sci. 2000 Oct;23(2):113-8. doi: 10.1016/s0955-3886(00)00075-8.
The aim of this retrospective study was to determine whether variations in the enumerated white cell contamination of leucocyte-depleted products was caused by the filter batch, the processing centre or by counting technology related issues. The influence of donor variation is also considered. The results suggest that for some red cell processes, variation is mainly the result of counting technology differences. Other products do not display similar trends though all leucodepletion processes may give rare high white count failures due to donor related issues, though defective filter batch cannot be excluded requiring continual review.
这项回顾性研究的目的是确定白细胞去除产品中白细胞计数污染的差异是由滤器批次、处理中心还是计数技术相关问题引起的。同时也考虑了供体差异的影响。结果表明，对于一些红细胞处理过程，差异主要是计数技术差异的结果。其他产品则没有显示出类似的趋势，尽管所有白细胞去除过程都可能因供体相关问题而出现罕见的高白细胞计数失败情况，不过也不能排除滤器批次有缺陷的可能性，因此需要持续审查。
