FitzGerald M P, Mollenhauer J, Brubaker L
Division of Urogynecology and Pelvic Reconstructive Surgery, Rush-Presbyterian-St Luke's Medical Center, Chicago, IL, USA.
Am J Obstet Gynecol. 2000 Oct;183(4):964-6. doi: 10.1067/mob.2000.107091.
Autologous rectus fascia is commonly used to construct suburethral slings for the treatment of genuine stress incontinence. This fascia performs well and has not been associated with clinical problems related to its choice as a sling material. However, the histologic appearance of such slings after implantation has not been documented.
At the time of revision of autologous rectus fascia suburethral slings in 5 patients, biopsy specimens of the slings were obtained and submitted for histologic examination. A specimen of rectus fascia before implantation was also obtained from a sixth patient who had no symptoms.
After implantation autologous rectus fascia slings remain viable. There is fibroblast proliferation, neovascularization, and remodeling of the graft. No evidence of inflammatory reaction or of graft degeneration was detected. A linear orientation of connective tissue and fibroblasts was seen in some areas, whereas other areas had remodeled to form tissue similar to noninflammatory scar.
Autologous rectus fascia slings undergo extensive remodeling after implantation.
自体腹直肌筋膜常用于构建尿道下吊带以治疗真性压力性尿失禁。这种筋膜效果良好，且未出现与将其作为吊带材料选择相关的临床问题。然而，植入后此类吊带的组织学表现尚无文献记载。
在对5例患者的自体腹直肌筋膜尿道下吊带进行翻修时，获取了吊带的活检标本并送检进行组织学检查。还从第6例无症状患者身上获取了植入前的腹直肌筋膜标本。
植入后自体腹直肌筋膜吊带仍存活。存在成纤维细胞增殖、新生血管形成以及移植物重塑。未检测到炎症反应或移植物退变的证据。在一些区域可见结缔组织和成纤维细胞呈线性排列，而其他区域已重塑形成类似于非炎性瘢痕的组织。
自体腹直肌筋膜吊带植入后会经历广泛的重塑。
