Nekhlyudov L, Gradzka M, Conti-Kelly A M, Greco T P
Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
Lupus. 2000;9(8):641-5. doi: 10.1191/096120300678828767.
Erythema nodosum is a dermatologic condition characterized by painful, erythematous nodules on the anterior surfaces of the lower extremities. Its association with a variety of conditions has been previously described. We present three cases of erythema nodosum in patients with elevated anticardiolipin antibodies. In one patient, a temporal relationship was seen in the simultaneous detection of antibodies and skin lesions. We propose an association between erythema nodosum and the antiphospholipid antibody syndrome (APS).
结节性红斑是一种皮肤病，其特征为下肢前侧出现疼痛性红斑结节。此前已有关于它与多种病症关联的描述。我们报告三例抗心磷脂抗体升高患者出现结节性红斑的病例。在一名患者中，抗体检测与皮肤病变的同时出现存在时间上的关联。我们提出结节性红斑与抗磷脂抗体综合征（APS）之间存在关联。
