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孤立性浅静脉反流的手术矫正可降低慢性下肢静脉溃疡的长期复发率。

Surgical correction of isolated superficial venous reflux reduces long-term recurrence rate in chronic venous leg ulcers.

作者信息

Barwell J R, Taylor M, Deacon J, Ghauri A S, Wakely C, Phillips L K, Whyman M R, Poskitt K R

机构信息

Department of Vascular Surgery, Cheltenham General Hospital, Gloucestershire, UK.

出版信息

Eur J Vasc Endovasc Surg. 2000 Oct;20(4):363-8. doi: 10.1053/ejvs.2000.1196.

Abstract

OBJECTIVES

surgical correction of isolated superficial venous reflux in ulcerated legs may reduce short term recurrence rates but the longer term benefits are unknown.

DESIGN

prospective non-randomised cohort study.

METHODS

consecutive patients with chronic leg ulcers were prospectively assessed at a one-stop clinic over a 4-year period from July 1995 to July 1999. All patients with ankle brachial pressure indices (ABPI)50.85 were initially treated with weekly four-layer bandaging. Venous duplex studies in all ulcerated legs assessed venous reflux pattern with surgery being offered to all those with isolated superficial reflux, of whom 56% accepted. Patients were advised to wear class two elastic compression stockings after healing.

RESULTS

766 legs in 669 patients were assessed. Six hundred and thirty-three legs had an ABPI50.85, 236 (39%) demonstrating isolated superficial venous reflux. Surgery was performed on 131 of these legs. Twelve and 24 week healing rates were 50% and 72% for operated legs and 62% and 74% for non-operated legs (p=0.67; Kaplan-Meier life table analysis). Recurrence rates at 1, 2 and 3 years were 14%, 20% and 26% for operated legs and 28%, 30% and 44% for non-operated legs (p=0.03; Kaplan-Meier life table analysis).

CONCLUSION

surgical correction of superficial venous reflux in legs with chronic leg ulceration may reduce ulcer recurrence rate at 1, 2 and 3 years.

摘要

目的

手术矫正溃疡腿孤立性浅静脉反流可能会降低短期复发率,但长期益处尚不清楚。

设计

前瞻性非随机队列研究。

方法

对1995年7月至1999年7月期间在一站式诊所连续就诊的慢性腿部溃疡患者进行前瞻性评估。所有踝肱压力指数(ABPI)≥0.85的患者最初接受每周一次的四层绷带包扎治疗。对所有溃疡腿进行静脉双功超声检查,评估静脉反流模式,为所有孤立性浅静脉反流患者提供手术治疗,其中56%的患者接受了手术。建议患者愈合后穿戴二级弹力袜。

结果

评估了669例患者的766条腿。633条腿的ABPI≥0.85,236条(39%)显示孤立性浅静脉反流。其中131条腿接受了手术。手术腿的12周和24周愈合率分别为50%和72%,非手术腿分别为62%和74%(p=0.67;Kaplan-Meier生存表分析)。手术腿1年、2年和3年的复发率分别为14%、20%和26%,非手术腿分别为28%、30%和44%(p=0.03;Kaplan-Meier生存表分析)。

结论

手术矫正慢性腿部溃疡患者的浅静脉反流可能会降低1年、2年和3年的溃疡复发率。

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