Barwell J R, Taylor M, Deacon J, Ghauri A S, Wakely C, Phillips L K, Whyman M R, Poskitt K R
Department of Vascular Surgery, Cheltenham General Hospital, Gloucestershire, UK.
Eur J Vasc Endovasc Surg. 2000 Oct;20(4):363-8. doi: 10.1053/ejvs.2000.1196.
surgical correction of isolated superficial venous reflux in ulcerated legs may reduce short term recurrence rates but the longer term benefits are unknown.
prospective non-randomised cohort study.
consecutive patients with chronic leg ulcers were prospectively assessed at a one-stop clinic over a 4-year period from July 1995 to July 1999. All patients with ankle brachial pressure indices (ABPI)50.85 were initially treated with weekly four-layer bandaging. Venous duplex studies in all ulcerated legs assessed venous reflux pattern with surgery being offered to all those with isolated superficial reflux, of whom 56% accepted. Patients were advised to wear class two elastic compression stockings after healing.
766 legs in 669 patients were assessed. Six hundred and thirty-three legs had an ABPI50.85, 236 (39%) demonstrating isolated superficial venous reflux. Surgery was performed on 131 of these legs. Twelve and 24 week healing rates were 50% and 72% for operated legs and 62% and 74% for non-operated legs (p=0.67; Kaplan-Meier life table analysis). Recurrence rates at 1, 2 and 3 years were 14%, 20% and 26% for operated legs and 28%, 30% and 44% for non-operated legs (p=0.03; Kaplan-Meier life table analysis).
surgical correction of superficial venous reflux in legs with chronic leg ulceration may reduce ulcer recurrence rate at 1, 2 and 3 years.
手术矫正溃疡腿孤立性浅静脉反流可能会降低短期复发率,但长期益处尚不清楚。
前瞻性非随机队列研究。
对1995年7月至1999年7月期间在一站式诊所连续就诊的慢性腿部溃疡患者进行前瞻性评估。所有踝肱压力指数(ABPI)≥0.85的患者最初接受每周一次的四层绷带包扎治疗。对所有溃疡腿进行静脉双功超声检查,评估静脉反流模式,为所有孤立性浅静脉反流患者提供手术治疗,其中56%的患者接受了手术。建议患者愈合后穿戴二级弹力袜。
评估了669例患者的766条腿。633条腿的ABPI≥0.85,236条(39%)显示孤立性浅静脉反流。其中131条腿接受了手术。手术腿的12周和24周愈合率分别为50%和72%,非手术腿分别为62%和74%(p=0.67;Kaplan-Meier生存表分析)。手术腿1年、2年和3年的复发率分别为14%、20%和26%,非手术腿分别为28%、30%和44%(p=0.03;Kaplan-Meier生存表分析)。
手术矫正慢性腿部溃疡患者的浅静脉反流可能会降低1年、2年和3年的溃疡复发率。