Girlich D, Naas T, Bellais S, Poirel L, Karim A, Nordmann P
Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris-Sud, 94275 Le Kremlin-Bicêtre, France.
Antimicrob Agents Chemother. 2000 Nov;44(11):3220-3. doi: 10.1128/AAC.44.11.3220-3223.2000.
Ten unrelated Hafnia alvei clinical isolates were grouped according to either their low-level and inducible cephalosporinase production or their high-level and constitutive cephalosporinase production phenotype. Their AmpC sequences shared 85 to 100% amino acid identity. The immediate genetic environment of ampC genes was conserved in H. alvei isolates but was different from that found in other ampC-possessing enterobacterial species.
十株无亲缘关系的蜂房哈夫尼亚菌临床分离株根据其低水平和诱导型头孢菌素酶产生或高水平和组成型头孢菌素酶产生表型进行分组。它们的AmpC序列具有85%至100%的氨基酸同一性。ampC基因的直接遗传环境在蜂房哈夫尼亚菌分离株中是保守的,但与在其他具有ampC的肠杆菌科细菌中发现的不同。