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本文引用的文献

1
Biochemical-genetic characterization and regulation of expression of an ACC-1-like chromosome-borne cephalosporinase from Hafnia alvei.来自蜂房哈夫尼亚菌的一种ACC-1样染色体携带头孢菌素酶的生化遗传特征及表达调控
Antimicrob Agents Chemother. 2000 Jun;44(6):1470-8. doi: 10.1128/AAC.44.6.1470-1478.2000.
2
A novel type of AmpC beta-lactamase, ACC-1, produced by a Klebsiella pneumoniae strain causing nosocomial pneumonia.一种由肺炎克雷伯菌菌株产生的新型AmpCβ-内酰胺酶ACC-1,该菌株导致医院获得性肺炎。
Antimicrob Agents Chemother. 1999 Aug;43(8):1924-31. doi: 10.1128/AAC.43.8.1924.
3
Integron- and carbenicillinase-mediated reduced susceptibility to amoxicillin-clavulanic acid in isolates of multidrug-resistant Salmonella enterica serotype typhimurium DT104 from French patients.来自法国患者的多重耐药鼠伤寒沙门氏菌血清型DT104分离株中整合子和羧苄青霉素酶介导的对阿莫西林-克拉维酸敏感性降低
Antimicrob Agents Chemother. 1999 May;43(5):1098-104. doi: 10.1128/AAC.43.5.1098.
4
Cloning, sequence analyses, expression, and distribution of ampC-ampR from Morganella morganii clinical isolates.摩根氏摩根菌临床分离株中AmpC - AmpR的克隆、序列分析、表达及分布
Antimicrob Agents Chemother. 1999 Apr;43(4):769-76. doi: 10.1128/AAC.43.4.769.
5
Salmonella enteritidis: AmpC plasmid-mediated inducible beta-lactamase (DHA-1) with an ampR gene from Morganella morganii.肠炎沙门氏菌:具有来自摩根氏摩根菌的ampR基因的AmpC质粒介导的可诱导β-内酰胺酶(DHA-1)
Antimicrob Agents Chemother. 1998 Sep;42(9):2352-8. doi: 10.1128/AAC.42.9.2352.
6
An extended-spectrum AmpC-type beta-lactamase obtained by in vitro antibiotic selection.通过体外抗生素筛选获得的超广谱AmpC型β-内酰胺酶。
FEMS Microbiol Lett. 1998 Aug 1;165(1):85-90. doi: 10.1111/j.1574-6968.1998.tb13131.x.
7
Structural and functional implications of sequence diversity of Pseudomonas aeruginosa genes oriC, ampC and fliC.铜绿假单胞菌基因oriC、ampC和fliC序列多样性的结构和功能影响
Electrophoresis. 1998 Apr;19(4):545-50. doi: 10.1002/elps.1150190414.
8
Resistance to oxyimino beta-lactams due to a mutation of chromosomal beta-lactamase in Citrobacter freundii.弗氏柠檬酸杆菌中由于染色体β-内酰胺酶突变导致对氧亚氨基β-内酰胺类抗生素耐药。
Microbiol Immunol. 1998;42(3):165-9. doi: 10.1111/j.1348-0421.1998.tb02267.x.
9
Sequences of homologous beta-lactamases from clinical isolates of Serratia marcescens with different substrate specificities.来自具有不同底物特异性的粘质沙雷氏菌临床分离株的同源β-内酰胺酶序列。
Antimicrob Agents Chemother. 1998 Jan;42(1):176-9. doi: 10.1128/AAC.42.1.176.
10
Molecular basis of beta-lactamase induction in bacteria.细菌中β-内酰胺酶诱导的分子基础
Antimicrob Agents Chemother. 1993 Feb;37(2):153-8. doi: 10.1128/AAC.37.2.153.

表达诱导型或组成型头孢他啶耐药表型的蜂房哈夫尼亚菌临床分离株中AmpC头孢菌素酶的异质性

Heterogeneity of AmpC cephalosporinases of Hafnia alvei clinical isolates expressing inducible or constitutive ceftazidime resistance phenotypes.

作者信息

Girlich D, Naas T, Bellais S, Poirel L, Karim A, Nordmann P

机构信息

Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris-Sud, 94275 Le Kremlin-Bicêtre, France.

出版信息

Antimicrob Agents Chemother. 2000 Nov;44(11):3220-3. doi: 10.1128/AAC.44.11.3220-3223.2000.

DOI:10.1128/AAC.44.11.3220-3223.2000
PMID:11036059
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC101639/
Abstract

Ten unrelated Hafnia alvei clinical isolates were grouped according to either their low-level and inducible cephalosporinase production or their high-level and constitutive cephalosporinase production phenotype. Their AmpC sequences shared 85 to 100% amino acid identity. The immediate genetic environment of ampC genes was conserved in H. alvei isolates but was different from that found in other ampC-possessing enterobacterial species.

摘要

十株无亲缘关系的蜂房哈夫尼亚菌临床分离株根据其低水平和诱导型头孢菌素酶产生或高水平和组成型头孢菌素酶产生表型进行分组。它们的AmpC序列具有85%至100%的氨基酸同一性。ampC基因的直接遗传环境在蜂房哈夫尼亚菌分离株中是保守的,但与在其他具有ampC的肠杆菌科细菌中发现的不同。