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与自身免疫性胰腺炎相关的皮质类固醇反应性糖尿病

Corticosteroid-responsive diabetes mellitus associated with autoimmune pancreatitis.

作者信息

Tanaka S, Kobayashi T, Nakanishi K, Okubo M, Murase T, Hashimoto M, Takeuchi K

出版信息

Lancet. 2000 Sep 9;356(9233):910-1. doi: 10.1016/S0140-6736(00)02684-2.

DOI:10.1016/S0140-6736(00)02684-2
PMID:11036899
Abstract

Autoimmune pancreatitis, which can be treated with corticosteroid therapy, has the potential to induce diabetes. In a cohort study of 2220 patients with suspected chronic pancreatitis, we found that all four patients with autoimmune chronic pancreatitis also had diabetes. Treatment with prednisolone subsequently improved insulin secretion and glycaemic control in these patients.

摘要

自身免疫性胰腺炎可用皮质类固醇疗法进行治疗,它有可能诱发糖尿病。在一项针对2220例疑似慢性胰腺炎患者的队列研究中,我们发现4例自身免疫性慢性胰腺炎患者均患有糖尿病。随后,泼尼松龙治疗改善了这些患者的胰岛素分泌和血糖控制。

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