Rybnikova E A, Rakitskaya V V, Shalyapina V G
Neuroendocrinology Laboratory, I.P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg.
Neurosci Behav Physiol. 2000 Sep-Oct;30(5):565-7. doi: 10.1007/BF02462616.
Studies reported here show that intrastriatal administration of corticoliberin to rats decreases the blood testosterone level. However, in conditions of chemical deficiency of dopaminergic transmission in the dorsal striatum induced by injection of 6-hydroxydopamine, the effect of this neurohormone did not appear. It is concluded that extrahypothalamic corticoliberin is involved in regulating the hormonal reproductive system acting via dopaminergic mechanisms.
此处报告的研究表明，向大鼠脑内纹状体注射促肾上腺皮质激素释放因子会降低血液中的睾酮水平。然而，在通过注射6-羟基多巴胺诱导的背侧纹状体多巴胺能传递化学缺陷的情况下，这种神经激素的作用并未显现。得出的结论是，下丘脑外促肾上腺皮质激素释放因子通过多巴胺能机制参与调节激素生殖系统。
