Mair T S, Walmsley J P, Phillips T J
The Bell Equine Veterinary Clinic, Maidstone, Kent, UK.
Equine Vet J. 2000 Sep;32(5):406-10. doi: 10.2746/042516400777591093.
The medical records of 45 horses treated for suspected squamous cell carcinoma of the penis and/or prepuce were reviewed. The age of 40 horses was known, and these had a mean age of 17.4 years. The duration of neoplasia was known for only 3 of the 45 horses. The results of histological evaluation of lesions, available for 35 horses, confirmed that the diseased tissue was squamous cell carcinoma. The location of gross neoplastic lesions was recorded for 43 horses; the glans penis was involved in 24 horses, the body of the penis or the inner lamina of the preputial fold in 27 horses, and the external fold of the prepuce in 10 horses. Surgical treatments of these horses included phallectomy (penile amputation) in 35 horses, segmental posthectomy in 4 horses, phallectomy plus segmental posthectomy in 2 horses, and en bloc resection of the penis, prepuce and superficial inguinal lymph nodes with penile retroversion in 4 cases. Short-term complications in the immediate postoperative period included preputial oedema and haemorrhage at the end of urination. One horse developed acute urinary retention because of severe urethral oedema. Long-term (>1 year) follow-up information was obtained for 31 horses. Neoplasia of the penis and/or prepuce recurred in 6 of these 31 horses (19%), and in 5 of these the recurrence necessitated euthanasia of the horse.
对45匹因疑似阴茎和/或包皮鳞状细胞癌而接受治疗的马匹的病历进行了回顾。已知40匹马的年龄，这些马的平均年龄为17.4岁。45匹马中只有3匹马的肿瘤形成持续时间已知。对35匹马的病变进行了组织学评估，结果证实病变组织为鳞状细胞癌。记录了43匹马大体肿瘤病变的位置；龟头受累的有24匹马，阴茎体或包皮褶内层受累的有27匹马，包皮外褶受累的有10匹马。这些马的手术治疗包括35匹马行阴茎切除术（阴茎截肢），4匹马行节段性包皮后切除术，2匹马行阴茎切除术加节段性包皮后切除术，4例整块切除阴茎、包皮和浅表腹股沟淋巴结并阴茎翻转。术后短期内的并发症包括包皮水肿和排尿末出血。一匹马因严重尿道水肿出现急性尿潴留。对31匹马进行了长期（>1年）随访。这31匹马中有6匹（19%）阴茎和/或包皮肿瘤复发，其中5匹马因复发需要实施安乐死。
