Savage M O, Wilkinson A R, Baum J D, Roberton N R
Arch Dis Child. 1975 Sep;50(9):709-13. doi: 10.1136/adc.50.9.709.
Savage, M. O., Wilkinson, A. R., Baum, J. D., Roberton, N. R. C. (1975). Archives of Disease in Childhood, 50, 709. Frusemide in respiratory distress syndrome. The effect of frusemide on urinary volume, urinary sodium excretion, and urinary calcium excretion in 7 premature infants with severe respiratory distress syndrome (RDS) has been studied. The results are compared with similar measurements on 13 infants of comparable gestational age and birthweight with less severe RDS who did not receive frusemide. The effect of frusemide on PaO2 and PaCO2 tensions in 5 infants with RDS was also investigated. Frusemide produced a fourfold increase in urinary volume and a tenfold increase in urinary sodium and urinary calcium excretion compared with the untreated group. It caused no improvement in blood gas tensions. The use of this diuretic for the routine management of RDS cannot be recommended.
萨维奇,M. O.,威尔金森,A. R.,鲍姆,J. D.,罗伯顿,N. R. C.(1975年)。《儿童疾病档案》,第50卷,第709页。速尿在呼吸窘迫综合征中的应用。研究了速尿对7例患有严重呼吸窘迫综合征(RDS)的早产儿尿量、尿钠排泄和尿钙排泄的影响。将结果与13例胎龄和出生体重相近、患有较轻RDS且未接受速尿治疗的婴儿的类似测量结果进行了比较。还研究了速尿对5例RDS婴儿动脉血氧分压(PaO2)和动脉血二氧化碳分压(PaCO2)的影响。与未治疗组相比,速尿使尿量增加了四倍,尿钠和尿钙排泄增加了十倍。它并未改善血气张力。不建议将这种利尿剂用于RDS的常规治疗。