对患有呼吸窘迫综合征的婴儿停止持续气道正压通气治疗。
Discontinuation of continuous positive airways pressure in infants with respiratory distress syndrome.
作者信息
Hegyi T, Hiatt I M
出版信息
Arch Dis Child. 1979 Sep;54(9):722-4. doi: 10.1136/adc.54.9.722.
Unexpected stability of arterial oxygen and carbon dioxide tensions occurred in infants recovering from respiratory distress syndrome (RDS) on the abrupt withdrawal of CPAP at 6 cmH2O pressure. 30 preterm infants (birthweights 880--3200 g gestational ages 29--38 weeks) were treated at a mean age of 10 hours and for a mean duration of 62 hours. CPAP was stopped when F1O2 requirement fell below 0.3, and stable PO2 was maintained for 4 hours. Discontinuation of CPAP at 6 cmH2O resulted in a mean change in PO2 from 66 to 64 mmHg (8.8 to 8.5 kPa) and a mean change in PCO2 from 41 to 40 mmHg (5.4 to 5.3 kPa). We conclude that this population of infants suffering from moderate RDS tolerated the abrupt withdrawal of CPAP, and that gradual reduction of pressure was unnecessary.
在6 cmH₂O压力下突然撤掉持续气道正压通气（CPAP）时，从呼吸窘迫综合征（RDS）恢复的婴儿出现了意外的动脉血氧和二氧化碳分压稳定性。30例早产儿（出生体重880 - 3200 g，胎龄29 - 38周）在平均10小时龄时接受治疗，平均治疗时长为62小时。当所需的吸入氧分数（F1O₂）降至0.3以下时停止CPAP，且稳定的动脉血氧分压（PO₂）维持了4小时。在6 cmH₂O时停止CPAP导致PO₂平均从66 mmHg降至64 mmHg（8.8 kPa降至8.5 kPa），二氧化碳分压（PCO₂）平均从41 mmHg降至40 mmHg（5.4 kPa降至5.3 kPa）。我们得出结论，这群患有中度RDS的婴儿能够耐受CPAP的突然撤掉，且无需逐渐降低压力。
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