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[Concepts for immune intervention in psoriasis vulgaris].

作者信息

Nestle F O

机构信息

Dermatologische Klinik des Universitätsspitals Zürich.

出版信息

Praxis (Bern 1994). 2000 Sep 14;89(37):1468-70.

PMID:11037618
Abstract

Psoriasis vulgaris is a chronic inflammatory skin condition with a genetic background. Activated T-cells and their secreted products seem to play an essential role in the induction as well as the promotion of the psoriatic plaque. We will focus on some recent concepts on the immunopathogenesis of psoriasis highlighting the role of dendritic cells as initiators of the disease as well as the recruitment of disease specific T-cells. Concepts for immunointervention will be introduced.

摘要

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