Le Pira F, Zappalà G, Giuffrida S, Lo Bartolo M L, Reggio E, Morana R, Lanaia F
Institute of Neurological Sciences, University of Catania, Italy.
Cephalalgia. 2000 Jun;20(5):475-8. doi: 10.1046/j.1468-2982.2000.00074.x.
Cognitive defects in migraine have been reported by several authors. These findings however, are controversial. In this study we carried out an investigation on 14 patients with migraine with aura and 16 with migraine without aura according to the International Headache Society criteria. They were submitted to a comprehensive battery of neuropsychological tests. The patients were compared with a control group not significantly different as to age, sex and education. Migraine subjects showed impaired neuropsychological performances only on some cognitive tests. Both groups of patients did worse than the control group on visuo-spatial memory tasks, while only migraineurs without aura showed significantly impaired verbal memory performances. The memory defects, both on visuo-spatial and on verbal cognitive tasks, could depend on an impaired recall mechanism. These memory difficulties seem related to strategically and organizationally defective aspects of learning.
几位作者报告了偏头痛患者存在认知缺陷。然而，这些研究结果存在争议。在本研究中，我们根据国际头痛协会的标准，对14例伴有先兆的偏头痛患者和16例无先兆的偏头痛患者进行了调查。他们接受了一系列全面的神经心理学测试。将这些患者与一个在年龄、性别和教育程度方面无显著差异的对照组进行比较。偏头痛患者仅在某些认知测试中表现出神经心理学表现受损。两组患者在视觉空间记忆任务上的表现均比对照组差，而只有无先兆的偏头痛患者表现出明显受损的言语记忆表现。视觉空间和言语认知任务上的记忆缺陷可能取决于回忆机制受损。这些记忆困难似乎与学习的策略性和组织性缺陷方面有关。
