Graff-Radford S B
The Pain Center of Cedars-Sinai Medical Center and UCLA School of Dentistry, Los Angeles, CA, USA.
Cephalalgia. 2000 Jun;20(5):515-7. doi: 10.1046/j.1468-2982.2000.00065.x.
A 48-year-old male suffering with SUNCT (severe unilateral neuralgiform headache with conjunctival injection and tearing, rhinorrhea and sub-clinical sweating) presented in 1996 after a 10-year history of multiple failed therapies. The symptoms included strictly left-sided ocular, as well as facial and temple pain. The pain attacks were burning, sharp, shooting and occurred 25 times daily, lasting 2 to 3 minutes with tearing and conjunctival injection. There was no associated nausea or vomiting, but there was photophobia. No other autonomic changes were reported and the pain was not triggerable. Initially Indocin (indomethacin) was tried without significant benefit. Gabapentin (Neurontin) was then started with improvement at 1800 mg per day. The patient was then lost to follow-up for 3 years, as he moved from the Los Angeles area. He returned in 1999 having stopped the gabapentin after his prescription ran out in 1996, reporting the pain returned immediately. Again gabapentin was prescribed and at 900 mg three times daily he has been pain free for 12 months.
一名48岁男性患有SUNCT（伴有结膜充血、流泪、鼻漏和亚临床出汗的严重单侧神经性头痛），在经历了10年多种治疗失败的病史后，于1996年前来就诊。症状包括严格局限于左侧的眼部、面部及颞部疼痛。疼痛发作呈烧灼样、尖锐、刺痛，每天发作25次，持续2至3分钟，伴有流泪和结膜充血。无恶心或呕吐，但有畏光症状。未报告其他自主神经变化，疼痛也无法诱发。起初试用消炎痛（吲哚美辛），但未获明显疗效。随后开始服用加巴喷丁（Neurontin），每日1800毫克时病情有所改善。之后患者因从洛杉矶地区搬走而失访3年。1999年他回来，称1996年处方药物用完后停用了加巴喷丁，疼痛随即复发。再次开具加巴喷丁，每日3次，每次900毫克，他已无痛12个月。
