Job J C, Chaussain J L, Franchimont P, Rolland A
Arch Fr Pediatr. 1975 May;32(5):471-7.
A case of precocious puberty in a 5-years old boy with a rapid increase of androgens, small testes, a high level of urinary bioassayable gonadotrophins, but no response of pituitary gonadotrophins of LH-RH injection. The cause was a mediastinal teratoma secreting chorionic gonadotrophin (HCG and beta subunit).
一名5岁男孩出现性早熟,雄激素迅速增加,睾丸较小,尿中生物活性促性腺激素水平升高,但注射LH-RH后垂体促性腺激素无反应。病因是纵隔畸胎瘤分泌绒毛膜促性腺激素(HCG和β亚基)。