Kremens B, Hauffa B P, Metz K
Abteilung für Hämatologie und Onkologie, Universität Essen, GHS.
Monatsschr Kinderheilkd. 1990 Oct;138(10):684-8.
Human chorionic gonadotropin (HCG) from a testicular tumor histologically diagnosed from its metastases to be a malignant teratoma induced elevated testosterone levels and subsequent precocious isosexual development in a 12-year-old boy. The endocrinologic consequences of long term ectopic HCG production in the prepubertal male are discussed. The case report illustrates the value of HCG serum levels as a marker for tumor activity.