Cimadevilla J M, Kaminsky Y, Fenton A, Bures J
Institute of Physiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
J Neurosci Methods. 2000 Oct 30;102(2):155-64. doi: 10.1016/s0165-0270(00)00288-0.
A modified model of the arena described by Bures et al. (Bures J, Fenton AA, Kaminsky Y, Zinyuk L. Place cells and place navigation, Proc. Natl. Acad. Sci. USA. 1997a;94:343-350) was applied to the place learning of adult male rats in two different avoidance paradigms. In the passive avoidance task rats exploring a stationary circular arena had to avoid a 60 degrees sector entering of which was punished by mild footshocks. Intramaze as well as extramaze cues could be used for adequate solution of this task. In the active avoidance paradigm rats were trained to avoid a room frame defined sector (e.g. North-East) of a slowly rotating arena the movement of which forced the animals to rely on extramaze cues and to ignore intramaze information. Rats had to find an active solution of the task since otherwise they were passively transported into the room frame defined punished zone. The suitability of these tasks for testing spatial abilities of rats is discussed.
布雷斯等人（布雷斯J、芬顿AA、卡明斯基Y、津尤克L。位置细胞与位置导航，《美国国家科学院院刊》。1997年a卷；94:343 - 350）所描述的改良型实验场模型被应用于成年雄性大鼠在两种不同回避范式下的位置学习。在被动回避任务中，探索固定圆形实验场的大鼠必须避开一个60度的扇形区域，进入该区域会受到轻微电击惩罚。迷宫内部以及迷宫外部的线索都可用于该任务的恰当解决。在主动回避范式中，大鼠被训练避开缓慢旋转实验场中由房间框架定义的扇形区域（如东北方向），实验场的旋转迫使动物依赖迷宫外部线索并忽略迷宫内部信息。大鼠必须找到该任务的主动解决办法，否则它们会被被动运送到由房间框架定义的受惩罚区域。讨论了这些任务对于测试大鼠空间能力的适用性。
