Stuchlik A, Fenton A A, Bures J
Institute of Physiology, Academy of Sciences, 14220 Prague, Czech Republic.
Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3537-42. doi: 10.1073/pnas.051630498.
The spatial orientation of vertebrates is implemented by two complementary mechanisms: allothesis, processing the information about spatial relationships between the animal and perceptible landmarks, and idiothesis, processing the substratal and inertial information produced by the animal's active or passive movement through the environment. Both systems allow the animal to compute its position with respect to perceptible landmarks and to the already traversed portion of the path. In the present study, we examined the properties of substratal idiothesis deprived of relevant exteroceptive information. Rats searching for food pellets in an arena formed by a movable inner disk and a peripheral immobile belt were trained in darkness to avoid a 60 degrees sector; rats that entered this sector received a mild foot shock. The punished sector was defined in the substratal idiothetic frame, and the rats had to determine the location of the shock sector with the use of substratal idiothesis only, because all putative intramaze cues were made irrelevant by angular displacements of the disk relative to the belt. Striking impairment of place avoidance by this "shuffling procedure" indicates that effective substratal idiothesis must be updated by exteroceptive intramaze cues.
异向定位，处理有关动物与可感知地标之间空间关系的信息；自体定位，处理动物在环境中主动或被动移动产生的基质和惯性信息。这两个系统都使动物能够计算其相对于可感知地标和已走过路径部分的位置。在本研究中，我们研究了缺乏相关外感受信息的基质自体定位的特性。在由可移动的内盘和周边固定带形成的场地中寻找食物颗粒的大鼠，在黑暗中接受训练以避开60度扇形区域；进入该扇形区域的大鼠会受到轻微的足部电击。受惩罚的扇形区域是在基质自体定位框架中定义的，大鼠必须仅使用基质自体定位来确定电击扇形区域的位置，因为圆盘相对于带子的角位移使所有假定的迷宫内部线索变得无关紧要。这种“洗牌程序”导致的位置回避显著受损表明，有效的基质自体定位必须通过迷宫内部的外感受线索来更新。
