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[糖尿病新的诊断标准与分类]

[New diagnostic criteria and classification of diabetes mellitus].

作者信息

Metelko Z, Pavlić-Renar I, Tomić M, Bratanić N

机构信息

Sveucilisna klinika Vuk Vrhovac, Zagreb.

出版信息

Lijec Vjesn. 2000 May-Jun;122(5-6):99-102.

PMID:11040530
Abstract

World Health Organisation (WHO) has recently proposed new diagnostic criteria and classification of diabetes mellitus. A major change in diagnostic criteria is lowering of diagnostic fasting plasma glucose level: level of 7.0 mM/L or more in two separate samples is sufficient for the diagnosis. Diagnostic criteria for plasma glucose in 120-min. of oral glucose tolerance test are unchanged. Newly recommended fasting level seems to correlate better with 120-min. value and to be a good marker of increased cardiovascular risk. The new classification describes impaired glucose regulation with two stages: impaired fasting glycaemia (plasma glucose of 6.1-7.0 mM/L) which is a new category and impaired glucose tolerance. Both subcategories are not real clinical entities, but markers of diabetic and cardiovascular risk. Diabetes mellitus, as a clinical entity, is separated in four classes: type 1, type 2, other specific types and gestational diabetes. Gestational diabetes includes any glucose intolerance in pregnancy. The Croatian Board for Diabetes Mellitus recommends acceptance of these criteria and classification for clinical use in the country and suggests that OGTT be performed for metabolic syndrome detection in cases of impaired fasting glycaemia.

摘要

世界卫生组织(WHO)最近提出了糖尿病的新诊断标准和分类。诊断标准的一个主要变化是降低了空腹血糖诊断水平:两次独立检测样本中血糖水平达到7.0 mM/L或更高即可确诊。口服葡萄糖耐量试验120分钟时的血糖诊断标准未变。新推荐的空腹血糖水平似乎与120分钟时的值相关性更好,并且是心血管风险增加的良好指标。新分类将血糖调节受损分为两个阶段:空腹血糖受损(血糖为6.1 - 7.0 mM/L),这是一个新类别,以及糖耐量受损。这两个亚类并非真正的临床实体,而是糖尿病和心血管风险的标志物。糖尿病作为一种临床实体,分为四类:1型、2型、其他特殊类型和妊娠期糖尿病。妊娠期糖尿病包括妊娠期间出现的任何糖耐量异常。克罗地亚糖尿病委员会建议在该国临床应用中采用这些标准和分类,并建议在空腹血糖受损的情况下进行口服葡萄糖耐量试验以检测代谢综合征。

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