Chiarioni G, Bassotti G, Monsignori A, Menegotti M, Salandini L, Di Matteo G, Vantini I, Whitehead W E
Division of Gastroenterological Rehabilitation, Valeggio sul Mincio Hospital, University of Verona Medical School, Italy.
Mayo Clin Proc. 2000 Oct;75(10):1015-9. doi: 10.4065/75.10.1015.
To evaluate anorectal and colonic function in a group of patients with anorexia nervosa complaining of chronic constipation.
Twelve women (age range, 19-29 years) meeting the criteria for anorexia nervosa and complaining of chronic constipation were recruited for the study. A group of 12 healthy women served as controls. Colonic transit time was measured by a radiopaque marker technique. Anorectal manometry and a test of rectal sensation were carried out with use of standard techniques to measure pelvic floor dysfunction. A subgroup of 8 patients was retested after an adequate refeeding program was completed.
Eight (66.7%) of 12 patients with anorexia nervosa had slow colonic transit times, while 5 (41.7%) had pelvic floor dysfunction. Colonic transit time normalized in the 8 patients who completed the 4-week refeeding program. However, pelvic floor dysfunction did not normalize in these patients.
Patients with anorexia nervosa who complain of constipation have anorectal motor abnormalities. Delayed colonic transit time is probably due to abnormal eating behavior.
评估一组患有神经性厌食症且抱怨慢性便秘的患者的肛肠和结肠功能。
招募了12名符合神经性厌食症标准且抱怨慢性便秘的女性（年龄范围19 - 29岁）进行研究。12名健康女性作为对照组。采用不透X线标志物技术测量结肠运输时间。使用标准技术进行肛肠测压和直肠感觉测试以测量盆底功能障碍。8名患者在完成充分的重新喂养计划后进行了复测。
12名神经性厌食症患者中有8名（66.7%）结肠运输时间缓慢，5名（41.7%）有盆底功能障碍。完成4周重新喂养计划的8名患者结肠运输时间恢复正常。然而，这些患者的盆底功能障碍并未恢复正常。
抱怨便秘的神经性厌食症患者存在肛肠运动异常。结肠运输时间延迟可能归因于异常的饮食行为。
