Bhosale S H, Jagtap T G, Naik C G
National Institute of Oceanography Dona Paula, Goa, India.
Mycopathologia. 1999;147(3):133-8. doi: 10.1023/a:1007184003971.
Crude aqueous methanol extracts obtained from 31 species of various marine organisms (including floral and faunal), were screened for their antifungal activity against food poisoning strains of Aspergillus. Seventeen species exhibited mild (+ = zone of inhibition 1-2 mm) to significant (+3 = zone of inhibition 3-5 mm) activity against one or the other strain under experiment. However, extracts of 12 species were active against all the three strains. Organisms like Salicornia brachiata (obligate halophyte), Sinularia leptocladus (Soft coral), Elysia grandifolia (Mollusks), Gorgonian sp. 2 and Haliclona sp. exhibited significant (inhibition zone of 3-5 mm) antifungal activity against one or the other strains. However, extracts of A. ilicifolius, Amphiroa sp., Poryphyra sp., Unidentified sponge, Suberites vestigium, Sinularia compressa, Sinularia sp., Sinularia maxima, Subergorgia suberosa, Echinogorgia pseudorassopo and Sabellaria cementifera were mild (inhibition zone of 1-2 mm) to moderate (inhibition zone of 2-3 mm) active against the respective strains. The growth of A. japonicus was significantly inhibited by the extracts of S. leptocladus (r = 0.992, p < 0.0001) and E. grandifolia (r = 0.989, p < 0.0001).
从31种不同海洋生物（包括植物和动物）中获得的粗制甲醇水提取物，针对食品中毒性曲霉菌株进行了抗真菌活性筛选。17种提取物对实验中的一种或另一种菌株表现出轻度（+ = 抑菌圈1 - 2毫米）到显著（+3 = 抑菌圈3 - 5毫米）的活性。然而，12种提取物对所有三种菌株均有活性。像盐角草（专性盐生植物）、细枝软珊瑚、大叶海天牛（软体动物）、柳珊瑚属物种2和扁海绵属物种等生物，对一种或另一种菌株表现出显著（抑菌圈3 - 5毫米）的抗真菌活性。然而，木果楝、叉节藻属物种、紫菜属物种、未鉴定的海绵、遗迹海绵、扁缩软珊瑚、软珊瑚属物种、大软珊瑚、亚侧柳珊瑚、假雷索波棘柳珊瑚和胶结苔藓虫的提取物对各自菌株的活性为轻度（抑菌圈1 - 2毫米）至中度（抑菌圈2 - 3毫米）。日本曲霉的生长受到细枝软珊瑚（r = 0.992，p < 0.0001）和大叶海天牛（r = 0.989，p < 0.0001）提取物的显著抑制。
