年龄对着床率影响的分析。
An analysis of the effect of age on implantation rates.
作者信息
Spandorfer S D, Chung P H, Kligman I, Liu H C, Davis O K, Rosenwaks Z
机构信息
Center for Reproductive Medicine and Infertility, New York Hospital/Cornell Medical Center, New York 10021, USA.
出版信息
J Assist Reprod Genet. 2000 Jul;17(6):303-6. doi: 10.1023/a:1009422725434.
Abstract
PURPOSE
To evaluate implantation rate as a function of age.
METHODS
A total of 1621 consecutive cycles of IVF were evaluated for implantation as a function of age at The New York Hospital/Cornell Medical Center.
RESULTS
An overall implantation rate of 23.3% (1328/5691) was found. The implantation rate as a function of age decreased in a nonlinear fashion. Implantation remained constant until the age of 35 and then decreased in a significantly, linear fashion by 2.77% per year (P < 0.001, R2 = 0.975). A formula to predict implantation rates for a given age was developed: Implantation rate = -119.352 + (9.985 x Age - (0.164 x Age2)).
CONCLUSIONS
We have demonstrated that implantation rates remain constant until the age of 35 at which time a linear decrease of 2.77% per year is observed.
摘要
目的
评估着床率与年龄的关系。
方法
在纽约医院/康奈尔医学中心，对1621个连续的体外受精周期进行评估，以研究着床率与年龄的关系。
结果
总体着床率为23.3%（1328/5691）。着床率与年龄的关系呈非线性下降。35岁之前着床率保持稳定，之后则以每年2.77%的显著线性速率下降（P < 0.001，R2 = 0.975）。得出了一个预测特定年龄着床率的公式：着床率 = -119.352 +（9.985×年龄 -（0.164×年龄²））。
结论
我们已证明，35岁之前着床率保持稳定，此后每年以2.77%的线性速率下降。
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