Marion J M, Alderson P O, Lefrak S S, Senior R M, Jacobs M H
Chest. 1976 Jan;69(1):5-9. doi: 10.1378/chest.69.1.5.
Twenty-seven patients underwent studies of unilateral lung function by the lateral-position test (LPT) and by computer-analyzed radionuclide imaging of ventilation and perfusion. The patients were divided into two groups, symmetric or asymmetric, on the basis of the physical examination of the chest and the chest radiograph. In patients with symmetry, the estimate of unilateral lung function by the LPT and isotopic estimates for unilateral lung volume, unilateral distribution of tidal volume, and unilateral perfusion, agreed within 2 percent, 4 percent, and 3 percent, respectively. In patients with asymmetry, the differences were 9 percent, 8 percent, and 13 percent. In settings of marked unilateral ventilation-perfusion imbalance, the LPT primarily reflected ventilation. Prediction of unilateral ventilatory function based upon the LPT and spirometric measurements agreed closely with unilateral ventilation determined isotopically by 133xenon, even in the presence of chronic obstructive lung disease. Our results confirm that the LPT provides valid information about unilateral lung function.
27例患者通过侧卧位试验（LPT）以及计算机分析的通气和灌注放射性核素成像进行了单侧肺功能研究。根据胸部体格检查和胸部X线片，将患者分为对称组或不对称组。在对称患者中，LPT对单侧肺功能的估计与单侧肺容积、潮气量单侧分布和单侧灌注的同位素估计值分别在2%、4%和3%以内相符。在不对称患者中，差异分别为9%、8%和13%。在明显的单侧通气-灌注失衡情况下，LPT主要反映通气情况。基于LPT和肺量计测量对单侧通气功能的预测与通过133氙同位素测定的单侧通气密切相符，即使在存在慢性阻塞性肺疾病的情况下也是如此。我们的结果证实，LPT可提供有关单侧肺功能的有效信息。
