Seki N, Azuma T, Yoshikawa T, Masuho Y, Muramatsu M, Saito T
Helix Research Institute, Kisarazu, Chiba, Japan.
J Hum Genet. 2000;45(5):318-22. doi: 10.1007/s100380070025.
Members of the RAB protein family regulate vesicular trafficking and reside in specific intercellular compartments. A new member of the RAB family was identified through a public database search, and its full-length cDNA was isolated from a human fetal brain cDNA library. The predicted protein product of the gene consists of 201 amino acid residues, and the protein has 86% similarity to human RAB9 at the amino acid level. We designated the new gene RAB9-like. Northern blot analysis showed that the gene was transcribed ubiquitously in various human tissues. A database search revealed that the gene is divided into three exons and spans approximately 7.2kb of the genome DNA of chromosome Xq22.1-q22.3 region.
