Muscardin L M, Pulsoni A, Cerroni L
Dermatologic Institute SS. Maria & Gallicano, Rome, Italy.
J Am Acad Dermatol. 2000 Nov;43(5 Pt 2):962-5.
Primary cutaneous plasmacytoma (PCP) is a rare cutaneous B-cell lymphoma. We report a new case of PCP and review data published in the literature. A 55-year-old man presented with 2 erythematous plaques on the upper trunk, showing histologic and immunohistochemical features of PCP. Staging investigations excluded extracutaneous manifestations of the disease. The patient was treated with melphalan and prednisone associated with local radiotherapy. Twenty-four months after the first presentation he is alive and well. Only 29 cases of PCP have been reported in the last 50 years. The main prognostic factor seems to be the clinical presentation (solitary vs multiple lesions). Solitary lesions of PCP may be treated conservatively by surgical excision or local radiotherapy.
原发性皮肤浆细胞瘤（PCP）是一种罕见的皮肤B细胞淋巴瘤。我们报告一例新的PCP病例，并回顾文献中发表的数据。一名55岁男性，上躯干出现2个红斑性斑块，显示出PCP的组织学和免疫组化特征。分期检查排除了该疾病的皮肤外表现。患者接受了美法仑和泼尼松联合局部放疗的治疗。首次就诊24个月后，他仍然健在。在过去50年中仅报告了29例PCP病例。主要的预后因素似乎是临床表现（单发与多发病变）。PCP的单发病变可通过手术切除或局部放疗进行保守治疗。
