Mosea A, Millwaters M
The Princess Alexandra Hospital, Harlow, United Kingdom.
The Princess Alexandra Hospital, Harlow, United Kingdom.
Int J Surg Case Rep. 2016;21:52-4. doi: 10.1016/j.ijscr.2016.02.016. Epub 2016 Feb 16.
Cutaneous extramedullary plasmacytoma without bone marrow involvement is very rare. We present a plasmacytoma on the scalp with an adjacent Bowenoid disease.
An 86 year old man presented to our unit with an ulcerated lump on the vertex of the scalp. Excisional biopsy showed plasmacytoma with adjacent Bowenoid actinic keratosis. Blood tests did not show any systemic multiple myeloma. However, skeletal survey showed possible osteolytic lesions in some areas. Sixteen months afterwards, the patient remains well on follow up.
As far as we know, this is the first reported case of a cutaneous plasma cell tumour next to an area of Bowenoid actinic keratosis. Relevant literature is investigated here for possible correlation.
Within the limitations of this study, solitary primary cutaneous plasmacytoma can be treated surgically with a favourable outcome. A hypothesis of correlation between Bowenoid actinic keratosis and plasmacytoma is investigated here. Further research is needed to confirm this finding.
无骨髓受累的皮肤髓外浆细胞瘤非常罕见。我们报告一例头皮浆细胞瘤伴相邻的鲍温样病。
一名86岁男性因头皮顶部溃疡性肿块前来我院就诊。切除活检显示为浆细胞瘤伴相邻的鲍温样光化性角化病。血液检查未显示任何系统性多发性骨髓瘤。然而，骨骼检查显示某些区域可能存在溶骨性病变。16个月后，患者随访情况良好。
据我们所知，这是首次报道的鲍温样光化性角化病区域旁的皮肤浆细胞肿瘤病例。在此对相关文献进行研究以探讨可能的相关性。
在本研究的局限性范围内，孤立性原发性皮肤浆细胞瘤可通过手术治疗，预后良好。在此探讨了鲍温样光化性角化病与浆细胞瘤之间相关性的假说。需要进一步研究来证实这一发现。
