Soriano C R, Martinez F E, Jorge S M
Department of Pediatrics, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Brazil.
J Pediatr Gastroenterol Nutr. 2000 Oct;31(4):387-90. doi: 10.1097/00005176-200010000-00011.
The cutaneous application of vegetable oil as a therapeutic practice and dietary coadjuvant has been described mainly in adult patients at risk for essential fatty acid deficiency. In the current study, the effects of cutaneous soybean oil application on somatic growth and plasma linoleic and arachidonic acid levels were examined in enterally fed preterm newborns.
Sixty consecutive preterm infants were chosen from patients admitted to the nursery. Infants were randomly assigned to one of two groups: the oil group, which was treated cutaneously with soybean oil, or the control group, which received no cutaneous treatment.
After 30 days, a significant increase in anthropometric parameters was observed in infants who received cutaneous oil, mainly in infants small for gestational age. An increase in linoleic acid level and a decrease in arachidonic acid level were seen in both groups but do not justify the difference found in growth rates in the control and oil groups.
Preterm infants treated cutaneously with soy oil showed better somatic growth than the control group. The factors leading to the present results, especially the response of the infants who were small for gestational age merit further evaluation.
植物油的皮肤应用作为一种治疗方法和饮食辅助手段，主要在有必需脂肪酸缺乏风险的成年患者中有所描述。在本研究中，对经肠道喂养的早产新生儿进行了皮肤涂抹大豆油对身体生长以及血浆亚油酸和花生四烯酸水平影响的研究。
从入住新生儿重症监护室的患者中连续选取60例早产儿。婴儿被随机分为两组之一：油组，接受大豆油皮肤治疗；对照组，不接受皮肤治疗。
30天后，接受皮肤用油治疗的婴儿，主要是小于胎龄儿，其人体测量参数有显著增加。两组均出现亚油酸水平升高和花生四烯酸水平降低的情况，但这并不能解释对照组和油组在生长速率上的差异。
经皮肤涂抹大豆油治疗的早产儿比对照组表现出更好的身体生长。导致目前结果的因素，尤其是小于胎龄儿的反应值得进一步评估。
