Kostara A, Roberts G J, Gelbier M
Department of Pediatric Dentistry, Eastman Dental Institute for Oral Health Care Sciences London, U.K.
Pediatr Dent. 2000 Sep-Oct;22(5):385-8.
This study was performed to compare Dental Age (DA) of children with Dystrophic Epidermolysis Bullosa recessiva (DEBr) with the DA of healthy children.
Orthopantomographs (OPG's) of children with DEBr were compared with those of healthy children. Dental maturity was estimated using Dermirjian's method. A total of 48 pairs of OPG's were compared.
There was a considerable range of variation in the difference between the chronological age and the dental age of both groups. This varied from minus 2 years 8 months to plus 3 years for the control children and minus 3 years 1 month to plus 3 years 4 months for the DEBr children. Despite this wider range the average DA of children with DEBr was statistically significantly delayed by 2 years 3 months.
The delay in dental developmental of children with DEBr may have an impact on the clinical management of these children.
本研究旨在比较隐性营养不良型大疱性表皮松解症（DEBr）患儿与健康儿童的牙龄（DA）。
将DEBr患儿的曲面体层片（OPG）与健康儿童的进行比较。采用德米尔坚法评估牙齿成熟度。共比较了48对OPG。
两组患儿的实际年龄与牙龄之差存在相当大的差异范围。对照组儿童的差异范围为负2年8个月至正3年，DEBr患儿的差异范围为负3年1个月至正3年4个月。尽管差异范围更广，但DEBr患儿的平均牙龄在统计学上显著延迟了2年3个月。
DEBr患儿牙齿发育延迟可能会对这些患儿的临床管理产生影响。
