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[沙眼——一种地方病及后地方病问题]

[Trachoma--an endemic and post-endemic problem].

作者信息

Bujger Z, Ekert M

机构信息

Klinika za ocne bolesti Medicinskog fakulteta, Klinicki bolnicki centar Zagreb.

出版信息

Lijec Vjesn. 2000 Jul-Aug;122(7-8):187-91.

Abstract

Trachoma is a specific chronic keratoconjunctivitis, characterized by follicular and papillary hyperplasia of conjunctiva, pannus, and cicatrization in the late stages of the disease. The cause of trachoma is a bacterium, Chlamydia trachomatis (serovar A, B, Ba and C). There are 146 million people in the world suffering from the active trachoma disease, and 5.9 million are blind because of it. WHO has set the goal to eliminate the blinding trachoma by the year 2020 (GET 2020 Program). The evaluation of the gravity of the disease has been made according to the Trachoma Simplified Grading System. In order to achieve the goal, it has used the SAFE strategy. The SAFE strategy comprises surgery for trichiasis, antibiotics, facial cleanliness and environmental improvement, especially in water supply and regulated sewage. The endemic trachoma in Croatia is a thing of past. Patients with active disease are rare, usually misdiagnosed and inadequately or insufficiently treated. A recent epidemic of another chlamydial (oculogenital sexually transmitted) disease has forced us to approach the diagnostics and treatment of chlamydial diseases with full responsibility.

摘要

沙眼是一种特殊的慢性角结膜炎,其特征为结膜滤泡和乳头增生、血管翳形成,以及疾病后期的瘢痕化。沙眼的病因是一种细菌,沙眼衣原体(血清型A、B、Ba和C)。全球有1.46亿人患有活动性沙眼疾病,其中590万人因此失明。世界卫生组织已设定目标,到2020年消除致盲性沙眼(“2020年全球消除沙眼致盲计划”)。疾病严重程度已根据沙眼简化分级系统进行评估。为实现该目标,采用了SAFE策略。SAFE策略包括倒睫手术、抗生素治疗、面部清洁和环境改善,特别是在供水和规范污水处理方面。克罗地亚的地方性沙眼已成为过去。活动性疾病患者很少见,通常被误诊,治疗不充分或不足。最近另一种衣原体(眼-生殖系统性传播)疾病的流行促使我们以高度负责的态度对待衣原体疾病的诊断和治疗。

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