血栓弹力图可识别凝血方面的性别差异。

Thromboelastography identifies sex-related differences in coagulation.

作者信息

Gorton H J, Warren E R, Simpson N A, Lyons G R, Columb M O

机构信息

Department of Anesthesia, St. James's University Hospital, Leeds, United Kingdom.

出版信息

Anesth Analg. 2000 Nov;91(5):1279-81. doi: 10.1097/00000539-200011000-00042.

DOI:10.1097/00000539-200011000-00042

PMID:11049922

Abstract

UNLABELLED

Thromboelastography is an in vitro, point-of-care monitor of whole blood coagulation. Thromboelastography studies have demonstrated a hypercoagulable state during pregnancy. Perhaps the hypercoagulability is attributable to female sex hormones. The aim of the study was to determine if sex, in addition to pregnancy, affected thromboelastography variables by studying male and female (pregnant and nonpregnant) volunteers. Thromboelastography showed significant (P:<0.01) differences in sex, with a significant (P: < 0. 0001) trend of increasing whole blood coagulability from men through nonpregnant to pregnant women. The thromboelastograph, used as a diagnostic tool, shows that women have more whole blood coagulability than men.

IMPLICATIONS

The thromboelastograph, used as a diagnostic tool, shows that women have more whole blood coagulability than men.

摘要

未标注

血栓弹力图是一种体外即时检测全血凝血功能的监测方法。血栓弹力图研究表明，孕期存在高凝状态。这种高凝状态可能归因于女性性激素。本研究的目的是通过对男性和女性（怀孕和未怀孕）志愿者进行研究，确定除怀孕外，性别是否会影响血栓弹力图变量。血栓弹力图显示性别间存在显著差异（P<0.01），从男性到未怀孕女性再到怀孕女性，全血凝固性呈显著（P<0.0001）上升趋势。作为一种诊断工具，血栓弹力图显示女性比男性具有更高的全血凝固性。