Karst Matthias, Rollnik Jens D, Fink Matthias, Reinhard Michaela, Piepenbrock Siegfried
Department of Anesthesiology, Medical School of Hannover, D-30623 Hannover, Germany Department of Neurology and Clinical Neurophysiology, Medical School of Hannover, D-30623 Hannover, Germany Department of Physical Medicine and Rehabilitation, Medical School of Hannover, D-30623 Hannover, Germany.
Pain. 2000 Nov;88(2):199-203. doi: 10.1016/S0304-3959(00)00315-8.
In order to examine the role of muscular mechanisms in chronic tension-type headache a study with needle acupuncture was performed. Needle acupuncture could be of therapeutic value because it has shown some positive effects in myofascial pain syndromes. We performed a double-blind, placebo-controlled study with 39 patients (mean age 49.0 years, SD=14.8) fulfilling the International Headache Society criteria for chronic tension-type headaches. Participants were randomly assigned to verum or placebo condition. Six weeks after end of treatment no significant differences between placebo and verum could be observed with respect to visual analogue scale and frequency of headache attacks. Nevertheless, pressure pain thresholds significantly increased for the verum group. The findings of our study support the hypothesis that peripheral mechanisms - such as increased muscle tenderness - only play a minor role in the pathogenesis of chronic tension-type headache.
为了研究肌肉机制在慢性紧张型头痛中的作用,我们进行了一项针对针刺疗法的研究。针刺疗法可能具有治疗价值,因为它在肌筋膜疼痛综合征中已显示出一些积极效果。我们对39名符合国际头痛协会慢性紧张型头痛标准的患者(平均年龄49.0岁,标准差=14.8)进行了一项双盲、安慰剂对照研究。参与者被随机分配到真治疗组或安慰剂组。治疗结束六周后,在视觉模拟量表和头痛发作频率方面,安慰剂组和真治疗组之间未观察到显著差异。然而,真治疗组的压痛阈值显著提高。我们的研究结果支持这样一种假设,即外周机制——如肌肉压痛增加——在慢性紧张型头痛的发病机制中仅起次要作用。