Baima C, Casetta G, Vella R, Tizzani A
Department of Urology (Head: Prof. A. Tizzani), University of Turin, Italy.
Urol Int. 2000;65(3):176-8. doi: 10.1159/000064868.
We report a case of a 75-year-old female with pheochromocytoma of the bladder. Clinical evaluation included ultrasonography, intravenous pyelography, CT scan, I-MIBG scintiscan. A transurethral resection was performed for a exophytic tumor of 2 cm diameter. The histological result indicated the diagnosis of bladder pheochromocytoma. Three years later the patient remains disease free. Preoperative diagnosis is established by determination of blood and urine levels of catecholamines and their metabolites is a nonspecific diagnostic tool. The sensitivity of CT scan is 82%. Iodine-methyliodobenzylguanidine (I-MIBG), used by scintiscanning, specifically accumulates in pheochromocytomas. Life-long follow-up is necessary to diagnose late recurrences.
我们报告一例75岁患有膀胱嗜铬细胞瘤的女性病例。临床评估包括超声检查、静脉肾盂造影、CT扫描、I-间碘苄胍闪烁扫描。对一个直径2cm的外生性肿瘤进行了经尿道切除术。组织学结果确诊为膀胱嗜铬细胞瘤。三年后该患者仍无疾病复发。通过测定血液和尿液中儿茶酚胺及其代谢产物水平进行术前诊断是一种非特异性诊断工具。CT扫描的敏感性为82%。用于闪烁扫描的碘-甲基碘苄胍(I-MIBG)特异性地聚集在嗜铬细胞瘤中。为诊断晚期复发,需要进行终身随访。