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[膀胱嗜铬细胞瘤。基于一例病例报告的诊断与治疗]

[Pheochromocytoma of the urinary bladder. Diagnosis and therapy based on a case report].

作者信息

Noldus J, Otto U, Conrad S, Klosterhalfen H

机构信息

Urologische Universitätsklinik Hamburg-Eppendorf.

出版信息

Urologe A. 1991 Jul;30(4):272-4.

PMID:1926677
Abstract

Micturition difficulties associated with unstable hypertension, tachycardia and profuse sweating could be a sign of pheochromocytoma of the urinary bladder. Of all pheochromocytomas, 10-36% are located extradrenally, in which case they are also referred to as paragangliomas, and 1-3% are found in the urinary bladder. The case history of a 44-year-old female patient with typical symptoms is described. Diagnosis required not only CT, NMR, excretory urography and MIBG scintigraphy, but also hormonal analyses. Histology reveals malignancy in up to 20%; it is thought that focal invasions of tumor into vessels and destruction of connective tissue might be pathognomonic. A precise history and careful diagnosis are necessary before a pheochromocytoma of the bladder can be disclosed and treated.

摘要

与不稳定型高血压、心动过速和多汗相关的排尿困难可能是膀胱嗜铬细胞瘤的征兆。在所有嗜铬细胞瘤中,10% - 36%位于肾上腺外,这种情况下它们也被称为副神经节瘤,1% - 3%位于膀胱。本文描述了一名有典型症状的44岁女性患者的病例史。诊断不仅需要CT、核磁共振成像、排泄性尿路造影和间碘苄胍闪烁显像,还需要进行激素分析。组织学显示高达20%为恶性;据认为肿瘤局部侵犯血管和结缔组织破坏可能具有诊断意义。在膀胱嗜铬细胞瘤得以诊断和治疗之前,准确的病史和仔细的诊断是必要的。

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