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[梅毒的被动血凝试验血清学诊断]

[Serologic diagnosis of syphilis by the passive hemagglutination test].

作者信息

Lefèvre J C, Dabernat H, Galtier M, Lareng M B, Lemozy J, Puel J, Auberdiac G

出版信息

Nouv Presse Med. 1975 Oct 18;4(35):2511-3.

PMID:1105415
Abstract

The passive haemagglutination test in the diagnosis of syphilis was used with: 139 sera posing serological problems, 965 sera from subjects with syphilis at all stages of the disease and non-syphilitics. The percentages of agreement seen both in comparison of THPA with the TPI (94,5 p.cent) and the FTA abs test (97 p.cent) demonstrate its high degree of specificity and sensitivity. The reaction may be performed rapidly on a routine basis and requires little in the way of specialised material. These qualities should lead, in the near future, to the adoption of the T.P.H.A. as a routine examination in all laboratories, reserving the use of the F.T.A. abs test and the T.P.I. for difficult cases.

摘要

被动血凝试验用于梅毒诊断,检测了139份存在血清学问题的血清、965份来自各期梅毒患者及非梅毒患者的血清。将梅毒螺旋体被动血凝试验(THPA)与梅毒螺旋体制动试验(TPI)比较,一致性为94.5%,与荧光密螺旋体抗体吸收试验(FTA abs试验)比较,一致性为97%,表明该试验具有高度特异性和敏感性。该反应可在常规条件下快速进行,所需特殊材料很少。这些特性在不久的将来应会促使所有实验室将梅毒螺旋体被动血凝试验作为常规检查,而将FTA abs试验和TPI用于疑难病例。

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