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[梅毒血清诊断中的被动血凝试验]

[Passive hemagglutination test in the serodiagnosis of syphilis].

作者信息

Georgescu M, Ionescu D, Dumitriu S

出版信息

Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Bacteriol Virusol Parazitol Epidemiol. 1979 Apr-Jun;24(2):109-13.

PMID:379958
Abstract

Passive haemagglutination test with pathogenic Treponema pallidum antigen in the serodiagnosis of syphilis, carried out on 752 sera (518 syphilitic patients and 234 subjects without evidence of syphilis) showed a greater general sensitivity as compared the cardiolipin tests and complement fixation test with Reiter protein antigen, and lower, to immunofluorescence (FTA--ABS). Its specificity is relatively lower than that of the cardiolopin and treponemal tests. Associated with the cardiolipin test it may be preferably used for the detection of syphilis, and moreover, passive haemagglutination may confirm the diagnosis in case of weak positive results with the FTA--ABS test. The latter is, however, essential for problem cases.

摘要

用致病性梅毒螺旋体抗原进行被动血凝试验以用于梅毒血清学诊断,对752份血清(518例梅毒患者和234例无梅毒证据的受试者)进行检测,结果显示与用牛心类脂质试验及用赖特蛋白抗原的补体结合试验相比,其总体敏感性更高,而低于免疫荧光试验(荧光密螺旋体抗体吸收试验)。其特异性相对低于牛心类脂质试验和密螺旋体试验。与牛心类脂质试验联合使用时,它可较好地用于梅毒检测,此外,被动血凝试验可在荧光密螺旋体抗体吸收试验结果弱阳性的情况下确诊。然而,对于疑难病例,荧光密螺旋体抗体吸收试验必不可少。

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