Olszowska M, Hlawaty M, Kostkiewicz M, Tomkiewicz L, Tracz W
Klinika Chorób Serca i Naczyń, Instytutu Kardiologii Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie.
Przegl Lek. 2000;57(5):255-7.
Myocardial velocity gradient is a new indicator of regional left ventricular contraction determined by a two dimensional tissue Doppler imaging technique. The main goal of this study was to compare myocardial velocity gradient in patients with old myocardial infarction and dilated cardiomyopathy to normal subjects. We assessed myocardial velocity gradient in 44 persons: 32 patients (19 men, 13 women, mean aged 51.2 +/- 6.1 years) and 12 healthy subjects (7 men, 5 women, mean age 49.3 +/- 8.3 years) who were divided into 4 groups. Group A--14 patients with old anteroseptal myocardial infarction, group B--7 patients with old posterior infarction, group C--11 patients with dilated cardiomyopathy and group D--12 healthy subjects. In normal subjects myocardial velocity gradient in the anteroseptal segment was mean 2.44 +/- 0.34 s-1 and in the posterior segment was 3.08 +/- 0.38 s-1. Myocardial velocity gradient in the infarct regions was significantly lower than in noninfarct regions as well as that in the corresponding regions in normal subjects. Gradient in the anteroseptal and posterior segments was in group A: 0.61 +/- 0.33 s-1 12.39 +/- 0.65 s-1, p < 0.001 respectively and group B: 2.11 +/- 0.45 s-1 10.91 +/- 0.34 s-1, p < 0.001 respectively. In patients with dilated cardiomyopathy gradient was significantly lower (nteroseptal segment 0.55 +/- 0.37 s-1, posterior segment 0.85 +/- 0.31 s-1) than that in normal subjects (p < 0.001).
Myocardial velocity gradient is a new indicator for the quantitative assessment of regional left ventricular contraction.
心肌速度梯度是一种通过二维组织多普勒成像技术测定的左心室局部收缩的新指标。本研究的主要目的是比较陈旧性心肌梗死患者、扩张型心肌病患者与正常受试者的心肌速度梯度。我们评估了44人的心肌速度梯度：32例患者（19名男性，13名女性，平均年龄51.2±6.1岁）和12名健康受试者（7名男性，5名女性，平均年龄49.3±8.3岁），他们被分为4组。A组——14例陈旧性前间隔心肌梗死患者，B组——7例陈旧性后壁梗死患者，C组——11例扩张型心肌病患者，D组——12名健康受试者。在正常受试者中，前间隔段心肌速度梯度平均为2.44±0.34 s-1，后壁段为3.08±0.38 s-1。梗死区域的心肌速度梯度显著低于非梗死区域以及正常受试者相应区域的心肌速度梯度。A组前间隔段和后壁段的梯度分别为：0.61±0.33 s-1、12.39±0.65 s-1，p<0.001；B组分别为：2.11±0.45 s-1、10.91±0.34 s-1，p<0.001。扩张型心肌病患者的梯度（前间隔段0.55±0.37 s-1，后壁段0.85±0.31 s-1）显著低于正常受试者（p<0.001）。
心肌速度梯度是定量评估左心室局部收缩的新指标。
